You will play an important role in the development and implementation of cellular assays to investigate the mechanism of action of lead drugs and apply Chemotype Evolution to identify novel drug leads for Carmot’s internal and partnered programs.
In this position you will screen custom compound libraries in cellular assays as well as develop new methods to understand MOA.
This requires working closely with scientists in biology and chemistry as part of a multidisciplinary team in a fast-paced environment.:Develop, conduct and analyze mechanistic pathway modulation assays in mammalian cells using western blots, ELISAs, reporter assays, qPCR and other techniquesGenerate and analyze primary cellular screening data to meet strict timelines and goalsTroubleshoot and optimize experiments to ensure high-quality data is obtainedCommunicate key findings at project meetings and make recommendations for follow-up studies and prioritizationExperience and Skills:BS or MS in cellular biology, biochemistry, molecular biology or related field with 3-5 years relevant experienceExperience with mammalian cell culture including transient and stable transfections is essential Prior experience interrogating the effects of small molecules on cell signaling pathways is highly desiredExpertise using liquid handling instruments and microplate formatsStrong organizational and communication skillsAbility to work both independently and within a multi-disciplinary environment Willingness to learn new skills and rapidly adapt to changing priorities for multiple projectsCarmot offers competitive salary, participation in our stock option plan, and comprehensivebenefits.
This position is located at our Berkeley site.
Carmot is an equal opportunity employer.
from Berkeley Job Site https://ift.tt/33zoANY
via IFTTT
No comments:
Post a Comment